Retatrutide: what phase 2 showed and what it did not

Started 17 January 2025 · 24 replies · 284 hearts · read 4.1k times

TacitaRome, IT · 17 January 2025

1.5 years ago

Retatrutide: what phase 2 showed and what it did not Writing it down partly to work out what I actually think.

Putting this here because I do not want to be sold anything, I want to know what is actually established.

I have written down what has actually happened, in order, because I find that more useful than my summary of it.

Here is where I am. The medication side has been more or less as described, and the part nobody prepared me for is everything around it: what to say to people, how to plan a week, and how to tell the difference between a thing to endure and a thing to raise.

I will report back either way, because I have been helped by other people's follow-ups more than by their questions.

IdrisCardiff, UK

It got worse before it got better for me, which I wish someone had said. About ten days of worse.

FlossieShrewsbury, UK

For what it is worth, the trial data on this is thinner than the confidence of the internet would suggest. Worth knowing when you read the posts.

BunnyWeston-super-Mare, UK

I am about four months behind you and I have been dreading exactly this, so thank you for writing it down before I got there.

SunilFacilitatorBirmingham, UK

What the reply above described happened to me too, in a slightly different order.

I will leave this open for a few more days and then add it to the circle's resources, because the answers here are better than anything I would have written.

21me too 2

MableBolton, UK

I did exactly the same and felt terrible about it. You have not done anything wrong.

AbramAmsterdam, NL

Practical, boring answer: write the three questions down before you go in. I have never once remembered them otherwise.

NevGrimsby, UK

the reply above — yes, and the bit that took me longest to accept was the next part.

Have you got anyone who can be with you when you do it? It made an enormous difference to me and I felt silly asking.

10me too 8

TamarPlymouth, UK

The thing that changed it for me was going slower, agreed with my prescriber. I am not suggesting you do that. I am saying the conversation exists.

FabianBasel, CH

Different experience here, for balance. Mine did not improve and in the end I stopped, and that was the right call for me. Both outcomes exist.

TobinCork, IE

#10

What the reply above described happened to me too, in a slightly different order.

The phrase that unlocked my appointment was asking what specifically she wanted me to watch for. It moved us from reassurance to a plan in about thirty seconds.

15me too 8

MorayElgin, UK

#11

Reading the reply above, I recognised more of that than I expected to.

Coming back to this a fortnight later to say it settled. Leaving the update because I hate reading threads that stop.

WellsChester, UK

#12

I am the person who had the frightening version of this. I went in, it was investigated, and it was not what anyone feared. Going in is the whole of my advice.

PolaGdańsk, PL

#13

My experience was very boring, which I offer as data. Some of us just get a dull time of it.

TacitaRome, IT

#14

What helped was lowering my own expectations of the week rather than trying to hold the week together.

6me too 7

IdrisCardiff, UK

#15

Please do not read the comments under news articles about this. I lost a fortnight to that.

FlossieShrewsbury, UK

#16

I asked my nurse the same question and she said something I have repeated ever since: that the aim is to keep you on treatment, not to get you up the schedule.

BunnyWeston-super-Mare, UK

#17

Similar here, and mine turned out to be a completely unrelated deficiency picked up on bloods.

13me too 2

IvorLlanelli, UK

#18

Gently disagreeing with the reply above, or rather adding the other half of it.

I have been in this circle a year and this question comes round every few months. It is not a silly question. It is the question.

MableBolton, UK

#19

Yes. All of this. I had the same in my third month and I remember thinking there was something specifically wrong with me, which there was not.

AbramAmsterdam, NL

#20

Mine lasted about seven weeks and then lifted over a few days. I cannot tell you why. I can tell you it lifted.

11me too 1

NevGrimsby, UK

#21

Two things that helped me, neither of them clever: small amounts more often, and drinking a lot more than felt necessary.

10me too 8

TamarPlymouth, UK

#22

I would take that to a clinician rather than to us, and I would do it this week. Not because it is definitely serious — because it is the sort of thing that is much easier to rule out than to worry about.

SunilFacilitatorBirmingham, UK

#23

Gently disagreeing with the reply above, or rather adding the other half of it.

I want to slow this down a little. There are four different answers flying about and they are all somebody's real experience, which makes them true and not necessarily relevant to the person who asked.

TobinCork, IE

#24

No advice, just recognition. That sounds exhausting and I am sorry you are in it.